| 1711 | The Town of Beaufort established. |
| 1861 | Union troops occupy Beaufort. |
| 1862 | Penn School founded to educate newly liberated slaves. |
| 1868 | The Mather School for daughters of former slaves established. |
| 1881 | Mrs. Mather deeds the property to the New England Baptist Missionary Association. |
| 1901 | First elementary class of three members graduates. |
| 1932 | Mather School high school program approved by the South Carolina State Department of Education as Mather Industrial School – 12 grades are now being taught. |
| 1954 | The Junior College Department organized to provide increased educational opportunities for high school graduates in the greater Beaufort area and allow male students to enroll. |
| 1955 | Mather School accredited by the Southern Association of Colleges and Schools. |
| 1956 | Mather Junior College graduates first class. |
| 1966 | Mather School one of three schools designated by the Office of Economic Opportunity for a pilot project designed to assist high school graduates in this section of South Carolina to overcome certain academic deficiencies before entering college. |
| 1967 | The Board of Trustees of the Mather School, in concurrence with the American Baptist Home Mission Societies vote to offer the campus and buildings to the South Carolina State Board of Education for use as a State Area Trade School and to effect a merger relationship with Benedict College, Columbia, South Carolina. |
| 1968 | Mather School concludes 100 years of unique educational service to the greater Beaufort area. The campus is given to the state of South Carolina as an area trade school. |
| 1969 | The South Carolina General Assembly transfers the administration of Beaufort Area Trade School from the Department of Education to the State Board for Technical and Comprehensive Education (SBTCE). |
| 1970 | The School becomes known as the Beaufort Regional Training Center. |
| 1972 | The Center becomes part of the State Technical College System under the State Board for Technical and Comprehensive Education and renamed the Beaufort Technical Education Center. |
| 1974 | State Board designates a four-county service area – Beaufort, Hampton, Jasper and Colleton counties. A branch campus is established in Hampton County. |
| 1978 | The Center is accredited by the Southern Association for Colleges and Schools. |
| 1979 | The Center’s name is changed to Beaufort Technical College. Off-Campus military education programs at the Marine Corps Air Station in Beaufort and the Marine Corps Recruit Depot at Parris Island are begun. |
| 1981 | Special Services, a program offering counseling to high risk, first- generation college students is begun. Part of the federal government TRIO programs. |
| 1982 | College receives funding for the Upward Bound Program, part of the federal government TRIO programs. Area high school students selected for special counseling and tutoring. |
| 1983 | The College’s Hilton Head Island Center is opened and the Beaufort Technical College Foundation is established. |
| 1984 | SACS Reaffirmation. |
| 1985 | College receives funding for Talent Search, a program providing career and college counseling in area high schools. Part of the federal government TRIO programs. College becomes one of only three colleges in the state to offer all three of the TRIO programs. |
| 1986 | Legislation is introduced to establish an area commission, a local government board for the College. |
| 1987 | Dr. Anne S. McNutt appointed President. |
| 1988 | College changes name to “ Technical College of the Lowcountry” to reflect its four-county service area. The Foundation is also renamed. |
| 1990 | Associate in Arts and Associate in Science degrees are offered. |
| 1991 | The Hampton Center is renamed H. Mungin Center in honor of Halbert Mungin, who served as Hampton County’s representative on the TCL Commission from 1987-1990. |
| 1992 | Converted from quarters to semesters. |
| 2005 | Groundbreaking for the New River Campus |
| 2006 | New River Campus opens doors for classes and dedicates campus |
